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This Annual Report provides an account of the main results achieved by the United Nations Office on Drugs and Crime, Regional Office for Central Asia (UNODC ROCA), in 2021. UNODC has stepped up efforts to help people in these challenging times, addressing emerging threats in line with human rights and gender equality standards, and the rule of law. Through our strategic interventions, we have contributed to strengthening peace, preventing conflict, and tackling the root causes and drivers of instability and violence.