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This paper stems from issues from a regional conference titled "Emerging Issues in the Sciences, Climate Change, Peace and Security and Information and Communication Technologies (ICTs), organized in Djibouti, in May 2017 by UNESCO Regional Office for Eastern Africa. The paper examines the issues and challenges of peace and security in Eastern Africa region and puts into perspective the regional higher education in terms of assess, quality, relevance, knowledge and skill products, and capacity to solve social challenges of society.